Effect of oral sodium bicarbonate supplementation on progression of chronic kidney disease in patients with chronic metabolic acidosis: study protocol for a randomized controlled trial (SoBic-Study)

BACKGROUND: Overt chronic metabolic acidosis in patients with chronic kidney disease develops after a drop of glomerular filtration rate to less than approximately 25 mL/min/1.73 m(2). The pathogenic mechanism seems to be a lack of tubular bicarbonate production, which in healthy individuals neutral...

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Detalles Bibliográficos
Autores principales: Gaggl, Martina, Cejka, Daniel, Plischke, Max, Heinze, Georg, Fraunschiel, Melanie, Schmidt, Alice, Hörl, Walter H, Sunder-Plassmann, Gere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729547/
https://www.ncbi.nlm.nih.gov/pubmed/23826760
http://dx.doi.org/10.1186/1745-6215-14-196

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