M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia

BACKGROUND: Microglia are the primary immune cells of the brain whose phenotype largely depends on their surrounding micro-environment. Microglia respond to a multitude of soluble molecules produced by a variety of brain cells. Macrophage colony-stimulating factor (M-CSF) is a cytokine found in the...

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Detalles Bibliográficos
Autores principales: Smith, Amy M, Gibbons, Hannah M, Oldfield, Robyn L, Bergin, Peter M, Mee, Edward W, Curtis, Maurice A, Faull, Richard L M, Dragunow, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729740/
https://www.ncbi.nlm.nih.gov/pubmed/23866312
http://dx.doi.org/10.1186/1742-2094-10-85

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