Loss of Survivin in the Prostate Epithelium Impedes Carcinogenesis in a Mouse Model of Prostate Adenocarcinoma

The inhibitor of apoptosis protein survivin is expressed in most cancers. Using the conditional PTEN deletion mouse model, we previously reported that survivin levels increase with prostate tumor growth. Here we evaluated the functional role of survivin in prostate tumor growth. First, we demonstrat...

Descripción completa

Detalles Bibliográficos
Autores principales: Adisetiyo, Helty, Liang, Mengmeng, Liao, Chun-Peng, Aycock-Williams, Ari, Cohen, Michael B., Xu, Shili, Neamati, Nouri, Conway, Edward M., Cheng, Chieh-Yang, Nikitin, Alexander Yu., Roy-Burman, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729965/
https://www.ncbi.nlm.nih.gov/pubmed/23936028
http://dx.doi.org/10.1371/journal.pone.0069484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729965/
https://www.ncbi.nlm.nih.gov/pubmed/23936028
http://dx.doi.org/10.1371/journal.pone.0069484

Ejemplares similares