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Loss of Survivin in the Prostate Epithelium Impedes Carcinogenesis in a Mouse Model of Prostate Adenocarcinoma
The inhibitor of apoptosis protein survivin is expressed in most cancers. Using the conditional PTEN deletion mouse model, we previously reported that survivin levels increase with prostate tumor growth. Here we evaluated the functional role of survivin in prostate tumor growth. First, we demonstrat...
Autores principales: | Adisetiyo, Helty, Liang, Mengmeng, Liao, Chun-Peng, Aycock-Williams, Ari, Cohen, Michael B., Xu, Shili, Neamati, Nouri, Conway, Edward M., Cheng, Chieh-Yang, Nikitin, Alexander Yu., Roy-Burman, Pradip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729965/ https://www.ncbi.nlm.nih.gov/pubmed/23936028 http://dx.doi.org/10.1371/journal.pone.0069484 |
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