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Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition
The multilayered epidermis is established through a stratification program, which is accompanied by a shift from symmetric toward asymmetric divisions (ACD), a process under tight control of the transcription factor p63. However, the physiological signals regulating p63 activity in epidermal morphog...
Autores principales: | Günschmann, Christian, Stachelscheid, Heike, Akyüz, Mehmet Deniz, Schmitz, Annika, Missero, Caterina, Brüning, Jens C., Niessen, Carien M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730059/ https://www.ncbi.nlm.nih.gov/pubmed/23906066 http://dx.doi.org/10.1016/j.devcel.2013.05.017 |
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