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NF-Y coassociates with FOS at promoters, enhancers, repetitive elements, and inactive chromatin regions, and is stereo-positioned with growth-controlling transcription factors
NF-Y, a trimeric transcription factor (TF) composed of two histone-like subunits (NF-YB and NF-YC) and a sequence-specific subunit (NF-YA), binds to the CCAAT motif, a common promoter element. Genome-wide mapping reveals 5000–15,000 NF-Y binding sites depending on the cell type, with the NF-YA and N...
Autores principales: | Fleming, Joseph D., Pavesi, Giulio, Benatti, Paolo, Imbriano, Carol, Mantovani, Roberto, Struhl, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730095/ https://www.ncbi.nlm.nih.gov/pubmed/23595228 http://dx.doi.org/10.1101/gr.148080.112 |
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