Cargando…

Comprehensive prediction in 78 human cell lines reveals rigidity and compactness of transcription factor dimers

The binding of transcription factors (TFs) to their specific motifs in genomic regulatory regions is commonly studied in isolation. However, in order to elucidate the mechanisms of transcriptional regulation, it is essential to determine which TFs bind DNA cooperatively as dimers and to infer the pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Jankowski, Aleksander, Szczurek, Ewa, Jauch, Ralf, Tiuryn, Jerzy, Prabhakar, Shyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730104/
https://www.ncbi.nlm.nih.gov/pubmed/23554463
http://dx.doi.org/10.1101/gr.154922.113