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Pigment Epithelium-Derived Factor Secreted from Retinal Pigment Epithelium Facilitates Apoptotic Cell Death of iPSC

We show that pigment epithelium-derived factor (PEDF), which is secreted from primary or iPSC-derived retinal pigment epithelium (RPE), dramatically inhibits the growth of iPSCs. PEDF is detected abundantly in culture supernatants of primary or iPSC-derived RPE. Apoptotic cell death is induced in iP...

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Detalles Bibliográficos
Autores principales:	Kanemura, Hoshimi, Go, Masahiro J., Nishishita, Naoki, Sakai, Noriko, Kamao, Hiroyuki, Sato, Yoji, Takahashi, Masayo, Kawamata, Shin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730169/ https://www.ncbi.nlm.nih.gov/pubmed/23903667 http://dx.doi.org/10.1038/srep02334

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