BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia

Paediatric B-precursor ALL is a highly curable disease, however, treatment resistance in some patients and the long-term toxic effects of current therapies pose the need for more targeted therapeutic approaches. We addressed the cytotoxic effect of JQ1, a highly selective inhibitor against the trans...

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Detalles Bibliográficos
Autores principales: Da Costa, D, Agathanggelou, A, Perry, T, Weston, V, Petermann, E, Zlatanou, A, Oldreive, C, Wei, W, Stewart, G, Longman, J, Smith, E, Kearns, P, Knapp, S, Stankovic, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730202/
https://www.ncbi.nlm.nih.gov/pubmed/23872705
http://dx.doi.org/10.1038/bcj.2013.24

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