Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A

Translation is regulated predominantly at the initiation phase by several signal transduction pathways that are often usurped in human cancers, including the PI3K/Akt/mTOR axis. mTOR exerts unique administration over translation by regulating assembly of eukaryotic initiation factor (eIF) 4F, a hete...

Descripción completa

Detalles Bibliográficos
Autores principales: Cencic, R, Robert, F, Galicia-Vázquez, G, Malina, A, Ravindar, K, Somaiah, R, Pierre, P, Tanaka, J, Deslongchamps, P, Pelletier, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730203/
https://www.ncbi.nlm.nih.gov/pubmed/23872707
http://dx.doi.org/10.1038/bcj.2013.25

Ejemplares similares

Ejemplares similares