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A Novel Three-Colour Fluorescence in Situ Hybridization Approach for the Detection of t(7;12)(q36;p13) in Acute Myeloid Leukaemia Reveals New Cryptic Three Way Translocation t(7;12;16)

The t(7;12)(q36;p13) translocation is a recurrent chromosome abnormality that involves the ETV6 gene on chromosome 12 and has been identified in 20–30% of infant patients with acute myeloid leukaemia (AML). The detection of t(7;12) rearrangements relies on the use of fluorescence in situ hybridizati...

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Detalles Bibliográficos
Autores principales: Naiel, Abdulbasit, Vetter, Michael, Plekhanova, Olga, Fleischman, Elena, Sokova, Olga, Tsaur, Grigory, Harbott, Jochen, Tosi, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730311/
https://www.ncbi.nlm.nih.gov/pubmed/24216708
http://dx.doi.org/10.3390/cancers5010281