Cargando…
Increasing Melanoma—Too Many Skin Cell Damages or Too Few Repairs?
Skin melanoma rates have been increasing for a long time in many Western countries. The object of this study was to apply modern problem-solving theory normally used to clear industrial problems to search for roots and causes of this medical question. Increasing cancer rates can be due to too many c...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730314/ https://www.ncbi.nlm.nih.gov/pubmed/24310359 http://dx.doi.org/10.3390/cancers5010184 |
_version_ | 1782279056955277312 |
---|---|
author | Hallberg, Örjan Johansson, Olle |
author_facet | Hallberg, Örjan Johansson, Olle |
author_sort | Hallberg, Örjan |
collection | PubMed |
description | Skin melanoma rates have been increasing for a long time in many Western countries. The object of this study was to apply modern problem-solving theory normally used to clear industrial problems to search for roots and causes of this medical question. Increasing cancer rates can be due to too many cell damage incidents or to too few repairs. So far, it has been assumed that the melanoma epidemic mainly is caused by increasing sun tanning habits. In order to explore this problem in more detail, we used cancer statistics from several countries over time and space. Detailed analysis of data obtained and a model study to evaluate the effects from increased damages or decreased repairs clearly indicate that the main reason behind the melanoma problem is a disturbed immune system. The possibility to introduce efficient corrective actions is apparent. |
format | Online Article Text |
id | pubmed-3730314 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-37303142013-08-05 Increasing Melanoma—Too Many Skin Cell Damages or Too Few Repairs? Hallberg, Örjan Johansson, Olle Cancers (Basel) Opinion Skin melanoma rates have been increasing for a long time in many Western countries. The object of this study was to apply modern problem-solving theory normally used to clear industrial problems to search for roots and causes of this medical question. Increasing cancer rates can be due to too many cell damage incidents or to too few repairs. So far, it has been assumed that the melanoma epidemic mainly is caused by increasing sun tanning habits. In order to explore this problem in more detail, we used cancer statistics from several countries over time and space. Detailed analysis of data obtained and a model study to evaluate the effects from increased damages or decreased repairs clearly indicate that the main reason behind the melanoma problem is a disturbed immune system. The possibility to introduce efficient corrective actions is apparent. MDPI 2013-02-18 /pmc/articles/PMC3730314/ /pubmed/24310359 http://dx.doi.org/10.3390/cancers5010184 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Opinion Hallberg, Örjan Johansson, Olle Increasing Melanoma—Too Many Skin Cell Damages or Too Few Repairs? |
title | Increasing Melanoma—Too Many Skin Cell Damages or Too Few Repairs? |
title_full | Increasing Melanoma—Too Many Skin Cell Damages or Too Few Repairs? |
title_fullStr | Increasing Melanoma—Too Many Skin Cell Damages or Too Few Repairs? |
title_full_unstemmed | Increasing Melanoma—Too Many Skin Cell Damages or Too Few Repairs? |
title_short | Increasing Melanoma—Too Many Skin Cell Damages or Too Few Repairs? |
title_sort | increasing melanoma—too many skin cell damages or too few repairs? |
topic | Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730314/ https://www.ncbi.nlm.nih.gov/pubmed/24310359 http://dx.doi.org/10.3390/cancers5010184 |
work_keys_str_mv | AT hallbergorjan increasingmelanomatoomanyskincelldamagesortoofewrepairs AT johanssonolle increasingmelanomatoomanyskincelldamagesortoofewrepairs |