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Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect
There is much ambiguity surrounding the diagnosis of nerve sheath tumors, including atypical neurofibroma and low-grade MPNST, and yet, the distinction between these entities designates either benign or malignant behavior and thus carries presumed profound prognostic importance that often guides tre...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730330/ https://www.ncbi.nlm.nih.gov/pubmed/24216989 http://dx.doi.org/10.3390/cancers5020519 |
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author | Bernthal, Nicholas M. Jones, Kevin B. Monument, Michael J. Liu, Ting Viskochil, David Randall, R. Lor |
author_facet | Bernthal, Nicholas M. Jones, Kevin B. Monument, Michael J. Liu, Ting Viskochil, David Randall, R. Lor |
author_sort | Bernthal, Nicholas M. |
collection | PubMed |
description | There is much ambiguity surrounding the diagnosis of nerve sheath tumors, including atypical neurofibroma and low-grade MPNST, and yet, the distinction between these entities designates either benign or malignant behavior and thus carries presumed profound prognostic importance that often guides treatment. This study reviews the diagnostic criteria used to designate atypical neurofibroma from low-grade MPNSTs and reviews existing literature the natural history of each of these tumors to see if the distinction is, in fact, of importance. |
format | Online Article Text |
id | pubmed-3730330 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-37303302013-08-05 Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect Bernthal, Nicholas M. Jones, Kevin B. Monument, Michael J. Liu, Ting Viskochil, David Randall, R. Lor Cancers (Basel) Review There is much ambiguity surrounding the diagnosis of nerve sheath tumors, including atypical neurofibroma and low-grade MPNST, and yet, the distinction between these entities designates either benign or malignant behavior and thus carries presumed profound prognostic importance that often guides treatment. This study reviews the diagnostic criteria used to designate atypical neurofibroma from low-grade MPNSTs and reviews existing literature the natural history of each of these tumors to see if the distinction is, in fact, of importance. MDPI 2013-05-08 /pmc/articles/PMC3730330/ /pubmed/24216989 http://dx.doi.org/10.3390/cancers5020519 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Bernthal, Nicholas M. Jones, Kevin B. Monument, Michael J. Liu, Ting Viskochil, David Randall, R. Lor Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect |
title | Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect |
title_full | Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect |
title_fullStr | Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect |
title_full_unstemmed | Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect |
title_short | Lost in Translation: Ambiguity in Nerve Sheath Tumor Nomenclature and Its Resultant Treatment Effect |
title_sort | lost in translation: ambiguity in nerve sheath tumor nomenclature and its resultant treatment effect |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730330/ https://www.ncbi.nlm.nih.gov/pubmed/24216989 http://dx.doi.org/10.3390/cancers5020519 |
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