Cargando…
Letrozole Potentiates Mitochondrial and Dendritic Spine Impairments Induced by β Amyloid
Reduced estrogens, either through aging or postsurgery breast cancer treatment with the oral nonsteroidal aromatase inhibitor letrozole, are linked with declined cognitive abilities. However, a direct link between letrozole and neuronal deficits induced by pathogenic insults associated with aging su...
Autores principales: | Chang, P. K.-Y., Boridy, S., McKinney, R. A., Maysinger, D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730361/ https://www.ncbi.nlm.nih.gov/pubmed/23956860 http://dx.doi.org/10.1155/2013/538979 |
Ejemplares similares
-
Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology
por: Chang, Philip K-Y, et al.
Publicado: (2015) -
Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons
por: Umeda, Tomohiro, et al.
Publicado: (2015) -
Erratum: Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons
por: Umeda, T, et al.
Publicado: (2016) -
Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells
por: Boridy, S, et al.
Publicado: (2014) -
LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB
por: Kawaguchi, Yuki, et al.
Publicado: (2022)