Protein Homeostasis Defects of Alanine-Glyoxylate Aminotransferase: New Therapeutic Strategies in Primary Hyperoxaluria Type I

Alanine-glyoxylate aminotransferase catalyzes the transamination between L-alanine and glyoxylate to produce pyruvate and glycine using pyridoxal 5′-phosphate (PLP) as cofactor. Human alanine-glyoxylate aminotransferase is a peroxisomal enzyme expressed in the hepatocytes, the main site of glyoxylat...

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Detalles Bibliográficos
Autores principales: Pey, Angel L., Albert, Armando, Salido, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730394/
https://www.ncbi.nlm.nih.gov/pubmed/23956997
http://dx.doi.org/10.1155/2013/687658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730394/
https://www.ncbi.nlm.nih.gov/pubmed/23956997
http://dx.doi.org/10.1155/2013/687658

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