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Mitochondrial DNA damage induces apoptosis in senescent cells
Senescence is a cellular response to damage and stress. The senescence response prevents cancer by suppressing the proliferation of cells with a compromised genome and contributes to optimal wound healing in normal tissues. Persistent senescent cells are also thought to drive aging and age-associate...
Autores principales: | Laberge, R-M, Adler, D, DeMaria, M, Mechtouf, N, Teachenor, R, Cardin, G B, Desprez, P-Y, Campisi, J, Rodier, F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730395/ https://www.ncbi.nlm.nih.gov/pubmed/23868060 http://dx.doi.org/10.1038/cddis.2013.199 |
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