Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a cytokine and a selective inducer of apoptosis in a range of tumour cells, but not in normal, untransformed cells. A large number of chemotherapeutics as well as biological agents are being tested for their potential to sensitise r...

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Detalles Bibliográficos
Autores principales: van Dijk, M, Halpin-McCormick, A, Sessler, T, Samali, A, Szegezdi, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730397/
https://www.ncbi.nlm.nih.gov/pubmed/23828565
http://dx.doi.org/10.1038/cddis.2013.214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730397/
https://www.ncbi.nlm.nih.gov/pubmed/23828565
http://dx.doi.org/10.1038/cddis.2013.214

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