Cargando…
Urocortin protects chondrocytes from NO-induced apoptosis: a future therapy for osteoarthritis?
Osteoarthritis (OA) is characterized by a loss of joint mobility and pain resulting from progressive destruction and loss of articular cartilage secondary to chondrocyte death and/ or senescence. Certain stimuli including nitric oxide (NO) and the pro-inflammatory cytokine tumor necrosis factor α (T...
Autores principales: | Intekhab-Alam, N Y, White, O B, Getting, S J, Petsa, A, Knight, R A, Chowdrey, H S, Townsend, P A, Lawrence, K M, Locke, I C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730405/ https://www.ncbi.nlm.nih.gov/pubmed/23846219 http://dx.doi.org/10.1038/cddis.2013.231 |
Ejemplares similares
-
New targets of urocortin-mediated cardioprotection
por: Barry, Seán P, et al.
Publicado: (2010) -
Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1
por: Lawrence, K. M., et al.
Publicado: (2017) -
Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis
por: Hwang, Hyun Sook, et al.
Publicado: (2015) -
Urocortin-1 Is Chondroprotective in Response to Acute Cartilage Injury via Modulation of Piezo1
por: Jones, Rebecca C., et al.
Publicado: (2022) -
Biomarkers of Chondrocyte Apoptosis and Autophagy in Osteoarthritis
por: Musumeci, Giuseppe, et al.
Publicado: (2015)