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Urocortin protects chondrocytes from NO-induced apoptosis: a future therapy for osteoarthritis?

Osteoarthritis (OA) is characterized by a loss of joint mobility and pain resulting from progressive destruction and loss of articular cartilage secondary to chondrocyte death and/ or senescence. Certain stimuli including nitric oxide (NO) and the pro-inflammatory cytokine tumor necrosis factor α (T...

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Detalles Bibliográficos
Autores principales: Intekhab-Alam, N Y, White, O B, Getting, S J, Petsa, A, Knight, R A, Chowdrey, H S, Townsend, P A, Lawrence, K M, Locke, I C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730405/
https://www.ncbi.nlm.nih.gov/pubmed/23846219
http://dx.doi.org/10.1038/cddis.2013.231

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