Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress

Sirtuin 3 (Sirt3), a major mitochondrial NAD(+)-dependent deacetylase, targets various mitochondrial proteins for lysine deacetylation and regulates important cellular functions such as energy metabolism, aging, and stress response. In this study, we identified the human 8-oxoguanine-DNA glycosylase...

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Detalles Bibliográficos
Autores principales: Cheng, Y, Ren, X, Gowda, A SP, Shan, Y, Zhang, L, Yuan, Y-S, Patel, R, Wu, H, Huber-Keener, K, Yang, J W, Liu, D, Spratt, T E, Yang, J-M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730425/
https://www.ncbi.nlm.nih.gov/pubmed/23868064
http://dx.doi.org/10.1038/cddis.2013.254

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