Cargando…

GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy

Glucose-regulated protein 78 (GRP78) is an endoplasmic reticulum (ER)-resident chaperone and a major regulator of the unfolded protein response (UPR). Accumulating evidence indicate that GRP78 is overexpressed in many cancer cell lines, and contributes to the invasion and metastasis in many human tu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Firczuk, M, Gabrysiak, M, Barankiewicz, J, Domagala, A, Nowis, D, Kujawa, M, Jankowska-Steifer, E, Wachowska, M, Glodkowska-Mrowka, E, Korsak, B, Winiarska, M, Golab, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730435/ https://www.ncbi.nlm.nih.gov/pubmed/23887632 http://dx.doi.org/10.1038/cddis.2013.265

Ejemplares similares

Low dose of GRP78-targeting subtilase cytotoxin improves the efficacy of photodynamic therapy in vivo
por: GABRYSIAK, MAGDALENA, et al.
Publicado: (2016)

Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer
por: Wachowska, Małgorzata, et al.
Publicado: (2011)

Selection of an optimal promoter for gene transfer in normal B cells
por: Winiarska, Magdalena, et al.
Publicado: (2017)

Escherichia coli Subtilase Cytotoxin
por: Paton, Adrienne W., et al.
Publicado: (2010)

Epigenetic remodeling combined with photodynamic therapy elicits anticancer immune responses
por: Wachowska, Malgorzata, et al.
Publicado: (2014)

Inhibition of autophagy sensitizes cancer cells to Photofrin-based photodynamic therapy
por: Domagala, Antoni, et al.
Publicado: (2018)

Novel Aspects of the SubA Subunit of the Subtilase Cytotoxin
por: Sessler, Katharina, et al.
Publicado: (2022)

Action of Shiga Toxin Type-2 and Subtilase Cytotoxin on Human Microvascular Endothelial Cells
por: Amaral, María M., et al.
Publicado: (2013)

Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells
por: Zhang, Lichao, et al.
Publicado: (2016)

Combined Action of Shiga Toxin Type 2 and Subtilase Cytotoxin in the Pathogenesis of Hemolytic Uremic Syndrome
por: Álvarez, Romina S., et al.
Publicado: (2021)

Variants of Escherichia coli Subtilase Cytotoxin Subunits Show Differences in Complex Formation In Vitro
por: Krause, Maike, et al.
Publicado: (2019)

Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes
por: Hu, Chih-Chi Andrew, et al.
Publicado: (2009)

Nitric oxide and peroxynitrite trigger and enhance release of neutrophil extracellular traps
por: Manda-Handzlik, Aneta, et al.
Publicado: (2019)

Duplication and diversification of a unique chromosomal virulence island hosting the subtilase cytotoxin in Escherichia coli ST58
por: Wyrsch, Ethan R., et al.
Publicado: (2020)

Statins impair glucose uptake in human cells
por: Nowis, Dominika, et al.
Publicado: (2014)

Ouabain Protects Human Renal Cells against the Cytotoxic Effects of Shiga Toxin Type 2 and Subtilase Cytotoxin
por: Amaral, María M., et al.
Publicado: (2017)

Subtilase cytotoxin from Shiga-toxigenic Escherichia coli impairs the inflammasome and exacerbates enteropathogenic bacterial infection
por: Tsutsuki, Hiroyasu, et al.
Publicado: (2022)

Occurrence of subtilase cytotoxin and relation with other virulence factors in verocytotoxigenic Escherichia coli isolated from food and cattle in Argentina
por: Velandia, Claudia V. Granobles, et al.
Publicado: (2011)

Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma
por: Trzeciecka, Anna, et al.
Publicado: (2015)

Effects of Escherichia Coli Subtilase Cytotoxin and Shiga Toxin 2 on Primary Cultures of Human Renal Tubular Epithelial Cells
por: Márquez, Laura B., et al.
Publicado: (2014)

A CRISPR Screen Using Subtilase Cytotoxin Identifies SLC39A9 as a Glycan-Regulating Factor
por: Yamaji, Toshiyuki, et al.
Publicado: (2019)

Subtilase cytotoxin induces a novel form of Lipocalin 2, which promotes Shiga-toxigenic Escherichia coli survival
por: Yahiro, Kinnosuke, et al.
Publicado: (2020)

Mitochondrial metabolic regulation by GRP78
por: Prasad, Manoj, et al.
Publicado: (2017)

GRP78 in lung cancer
por: Xia, Shengkai, et al.
Publicado: (2021)

Targeting Epigenetic Processes in Photodynamic Therapy-Induced Anticancer Immunity
por: Wachowska, Malgorzata, et al.
Publicado: (2015)

Comparative Characterization of Shiga Toxin Type 2 and Subtilase Cytotoxin Effects on Human Renal Epithelial and Endothelial Cells Grown in Monolayer and Bilayer Conditions
por: Álvarez, Romina S., et al.
Publicado: (2016)

GRP78: A cell's response to stress
por: Ibrahim, Ibrahim M., et al.
Publicado: (2019)

GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells
por: Ibanez, Jorge, et al.
Publicado: (2023)

Differential requirement of GRP94 and GRP78 in mammary gland development
por: Zhu, Genyuan, et al.
Publicado: (2014)

Dynamic Changes in the Ability to Release Neutrophil ExtraCellular Traps in the Course of Childhood Acute Leukemias
por: Ostafin, Magdalena, et al.
Publicado: (2021)

Crosstalk between Human Microvascular Endothelial Cells and Tubular Epithelial Cells Modulates Pro-Inflammatory Responses Induced by Shiga Toxin Type 2 and Subtilase Cytotoxin
por: Álvarez, Romina S., et al.
Publicado: (2019)

Ultrasensitive Detection of GRP78 in Exosomes and Observation of Migration and Proliferation of Cancer Cells by Application of GRP78-Containing Exosomes
por: Tsurusawa, Naoko, et al.
Publicado: (2022)

GRP78 Is a Targetable Receptor on Cancer and Stromal Cells
por: Araujo, Nathalia, et al.
Publicado: (2018)

Grp78 promotes the invasion of hepatocellular carcinoma
por: Su, Rongjian, et al.
Publicado: (2010)

GRP78 at the Centre of the Stage in Cancer and Neuroprotection
por: Casas, Caty
Publicado: (2017)

Targeting the GRP78 Pathway for Cancer Therapy
por: Lu, Guanhua, et al.
Publicado: (2020)

Molecular analysis of subtilase cytotoxin genes of food-borne Shiga toxin-producing Escherichia coli reveals a new allelic subAB variant
por: Funk, Joschua, et al.
Publicado: (2013)

GRP78 targeting: Hitting two birds with a stone
por: Elfiky, Abdo A., et al.
Publicado: (2020)

Expression and release of glucose-regulated protein-78 (GRP78) in multiple myeloma
por: Steiner, Normann, et al.
Publicado: (2017)

The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness
por: Chen, Hsin-Ying, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_fd4ku6l7tr4vuoajkksdgruca4