Cargando…

Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements

Suppression of duplication-mediated gross chromosomal rearrangements (GCRs) is essential to maintain genome integrity in eukaryotes. Here we report that SUMO ligase Mms21 has a strong role in suppressing GCRs in Saccharomyces cerevisiae, while Siz1 and Siz2 have weaker and partially redundant roles....

Descripción completa

Detalles Bibliográficos
Autores principales:	Albuquerque, Claudio P., Wang, Guoliang, Lee, Nancy S., Kolodner, Richard D., Putnam, Christopher D., Zhou, Huilin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731205/ https://www.ncbi.nlm.nih.gov/pubmed/23935535 http://dx.doi.org/10.1371/journal.pgen.1003670

Ejemplares similares

Correction: Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements
por: Albuquerque, Claudio P., et al.
Publicado: (2016)

SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements
por: Liang, Jason, et al.
Publicado: (2018)

Physical and Genetic Interactions Between Uls1 and the Slx5–Slx8 SUMO-Targeted Ubiquitin Ligase
por: Tan, Wei, et al.
Publicado: (2013)

Crystal structure and SUMO binding of Slx1-Slx4 complex
por: Lian, Fu-Ming, et al.
Publicado: (2016)

Specific pathways prevent duplication-mediated genome rearrangements
por: Putnam, Christopher D., et al.
Publicado: (2009)

Recruitment of a SUMO isopeptidase to rDNA stabilizes silencing complexes by opposing SUMO targeted ubiquitin ligase activity
por: Liang, Jason, et al.
Publicado: (2017)

Post-Replication Repair Suppresses Duplication-Mediated Genome Instability
por: Putnam, Christopher D., et al.
Publicado: (2010)

Shared and distinct roles of Esc2 and Mms21 in suppressing genome rearrangements and regulating intracellular sumoylation
por: Suhandynata, Raymond T., et al.
Publicado: (2021)

Slx5-Slx8 ubiquitin ligase targets active pools of the Yen1 nuclease to limit crossover formation
por: Talhaoui, Ibtissam, et al.
Publicado: (2018)

SUMO-targeted ubiquitin ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin
por: Ohkuni, Kentaro, et al.
Publicado: (2016)

APC/C (Cdh1p) and Slx5p/Slx8p ubiquitin ligases confer resistance to aminoglycoside hygromycin B in Saccharomyces cerevisiae
por: Doss, Ellen M., et al.
Publicado: (2022)

Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease
por: Gaur, Vineet, et al.
Publicado: (2015)

Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex
por: Yin, Jinhu, et al.
Publicado: (2016)

Genome maintenance in Saccharomyces cerevisiae: the role of SUMO and SUMO-targeted ubiquitin ligases
por: Jalal, Deena, et al.
Publicado: (2017)

A SUMO-targeted ubiquitin ligase is involved in the degradation of the nuclear pool of the SUMO E3 ligase Siz1
por: Westerbeck, Jason W., et al.
Publicado: (2014)

SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites
por: González-Prieto, Román, et al.
Publicado: (2015)

Recognition and processing of branched DNA substrates by Slx1–Slx4 nuclease
por: Gaur, Vineet, et al.
Publicado: (2019)

Structure specific DNA recognition by the SLX1–SLX4 endonuclease complex
por: Xu, Xiang, et al.
Publicado: (2021)

SUMO-Targeted Ubiquitin Ligase, Rad60, and Nse2 SUMO Ligase Suppress Spontaneous Top1–Mediated DNA Damage and Genome Instability
por: Heideker, Johanna, et al.
Publicado: (2011)

Slx8 Removes Pli1-Dependent Protein-SUMO Conjugates Including SUMOylated Topoisomerase I to Promote Genome Stability
por: Steinacher, Roland, et al.
Publicado: (2013)

Slx5/Slx8‐dependent ubiquitin hotspots on chromatin contribute to stress tolerance
por: Höpfler, Markus, et al.
Publicado: (2019)

DNA Repair Pathway Selection Caused by Defects in TEL1, SAE2, and De Novo Telomere Addition Generates Specific Chromosomal Rearrangement Signatures
por: Putnam, Christopher D., et al.
Publicado: (2014)

Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain
por: Sriramachandran, Annie M., et al.
Publicado: (2019)

Cancer-Associated Dysregulation of Sumo Regulators: Proteases and Ligases
por: Lara-Ureña, Nieves, et al.
Publicado: (2022)

A SUMO-interacting motif activates budding yeast ubiquitin ligase Rad18 towards SUMO-modified PCNA
por: Parker, Joanne L., et al.
Publicado: (2012)

Purification of the yeast Slx5–Slx8 protein complex and characterization of its DNA-binding activity
por: Yang, Litao, et al.
Publicado: (2006)

SLX4IP acts with SLX4 and XPF–ERCC1 to promote interstrand crosslink repair
por: Zhang, Huimin, et al.
Publicado: (2019)

Mutations of the SLX4 gene in Fanconi anemia
por: Kim, Yonghwan, et al.
Publicado: (2011)

Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination
por: Qiao, Huanyu, et al.
Publicado: (2014)

Genome rearrangements with duplications
por: Bader, Martin
Publicado: (2010)

Tomosyn Interacts with the SUMO E3 Ligase PIASγ
por: Geerts, Cornelia J., et al.
Publicado: (2014)

SUMO-Targeted Ubiquitin Ligases and Their Functions in Maintaining Genome Stability
por: Chang, Ya-Chu, et al.
Publicado: (2021)

PIAS1 Is a GATA4 SUMO Ligase That Regulates GATA4-Dependent Intestinal Promoters Independent of SUMO Ligase Activity and GATA4 Sumoylation
por: Belaguli, Narasimhaswamy S., et al.
Publicado: (2012)

Correction: PIAS1 Is a GATA4 SUMO Ligase That Regulates GATA4-Dependent Intestinal Promoters Independent of SUMO Ligase Activity and GATA4 Sumoylation
por: Belaguli, Narasimhaswamy S., et al.
Publicado: (2012)

Cooperativity of the SUMO and Ubiquitin Pathways in Genome Stability
por: Nie, Minghua, et al.
Publicado: (2016)

Whole‐genome duplications followed by tandem duplications drive diversification of the protein modifier SUMO in Angiosperms
por: Hammoudi, Valentin, et al.
Publicado: (2016)

The Biology of SUMO-Targeted Ubiquitin Ligases in Drosophila Development, Immunity, and Cancer
por: Abed, Mona, et al.
Publicado: (2018)

The Role of SUMO E3 Ligases in Signaling Pathway of Cancer Cells
por: Shi, Xiaoxia, et al.
Publicado: (2022)

Preserving genome integrity: The vital role of SUMO-targeted ubiquitin ligases
por: Han, Jinhua, et al.
Publicado: (2023)

Cooperative Control of Holliday Junction Resolution and DNA Repair by the SLX1 and MUS81-EME1 Nucleases
por: Castor, Dennis, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_o8qlmmmgtsdgkoduccn14k8fj1