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Cited1 Deficiency Suppresses Intestinal Tumorigenesis
Conditional deletion of Apc in the murine intestine alters crypt-villus architecture and function. This process is accompanied by multiple changes in gene expression, including upregulation of Cited1, whose role in colorectal carcinogenesis is unknown. Here we explore the relevance of Cited1 to inte...
Autores principales: | Méniel, Valérie, Song, Fei, Phesse, Toby, Young, Madeleine, Poetz, Oliver, Parry, Lee, Jenkins, John R., Williams, Geraint T., Dunwoodie, Sally L., Watson, Alastair, Clarke, Alan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731217/ https://www.ncbi.nlm.nih.gov/pubmed/23935526 http://dx.doi.org/10.1371/journal.pgen.1003638 |
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