The Wilms Tumor Gene, Wt1, Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans

Azoospermia is one of the major reproductive disorders which cause male infertility in humans; however, the etiology of this disease is largely unknown. In the present study, six missense mutations of WT1 gene were detected in 529 human patients with non-obstructive azoospermia (NOA), indicating a s...

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Detalles Bibliográficos
Autores principales: Wang, Xiao Na, Li, Ze Song, Ren, Yu, Jiang, Tao, Wang, Ya Qing, Chen, Min, Zhang, Jun, Hao, Jian Xiu, Wang, Yan Bo, Sha, Ri Na, Huang, Yi, Liu, Xiao, Hu, Jing Chu, Sun, Guang Qing, Li, Hong Gang, Xiong, Cheng Liang, Xie, Jun, Jiang, Zhi Mao, Cai, Zhi Ming, Wang, Jun, Wang, Jian, Huff, Vicki, Gui, Yao Ting, Gao, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731222/
https://www.ncbi.nlm.nih.gov/pubmed/23935527
http://dx.doi.org/10.1371/journal.pgen.1003645

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