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Distinct Binding and Immunogenic Properties of the Gonococcal Homologue of Meningococcal Factor H Binding Protein
Neisseria meningitidis is a leading cause of sepsis and meningitis. The bacterium recruits factor H (fH), a negative regulator of the complement system, to its surface via fH binding protein (fHbp), providing a mechanism to avoid complement-mediated killing. fHbp is an important antigen that elicits...
Autores principales: | Jongerius, Ilse, Lavender, Hayley, Tan, Lionel, Ruivo, Nicola, Exley, Rachel M., Caesar, Joseph J. E., Lea, Susan M., Johnson, Steven, Tang, Christoph M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731240/ https://www.ncbi.nlm.nih.gov/pubmed/23935503 http://dx.doi.org/10.1371/journal.ppat.1003528 |
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