Cargando…

Distinct Binding and Immunogenic Properties of the Gonococcal Homologue of Meningococcal Factor H Binding Protein

Neisseria meningitidis is a leading cause of sepsis and meningitis. The bacterium recruits factor H (fH), a negative regulator of the complement system, to its surface via fH binding protein (fHbp), providing a mechanism to avoid complement-mediated killing. fHbp is an important antigen that elicits...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jongerius, Ilse, Lavender, Hayley, Tan, Lionel, Ruivo, Nicola, Exley, Rachel M., Caesar, Joseph J. E., Lea, Susan M., Johnson, Steven, Tang, Christoph M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731240/ https://www.ncbi.nlm.nih.gov/pubmed/23935503 http://dx.doi.org/10.1371/journal.ppat.1003528

Ejemplares similares

Neisseria cinerea Expresses a Functional Factor H Binding Protein Which Is Recognized by Immune Responses Elicited by Meningococcal Vaccines
por: Lavender, Hayley, et al.
Publicado: (2017)

A gonococcal homologue of meningococcal γ-glutamyl transpeptidase gene is a new type of bacterial pseudogene that is transcriptionally active but phenotypically silent
por: Takahashi, Hideyuki, et al.
Publicado: (2005)

Thermoregulation of Meningococcal fHbp, an Important Virulence Factor and Vaccine Antigen, Is Mediated by Anti-ribosomal Binding Site Sequences in the Open Reading Frame
por: Loh, Edmund, et al.
Publicado: (2016)

Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules
por: Johnson, Steven, et al.
Publicado: (2012)

Correction: Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules
por: Johnson, Steven, et al.
Publicado: (2013)

Gonococcal Vaccine Development: Lessons from Group B Meningococcal Vaccines
Publicado: (2017)

Meningococcal Factor H Binding Protein fHbpd184 Polymorphism Influences Clinical Course of Meningococcal Meningitis
por: Piet, Jurgen R., et al.
Publicado: (2012)

Gonococcal pili. Primary structure and receptor binding domain
Publicado: (1984)

Genetic Similarity of Gonococcal Homologs to Meningococcal Outer Membrane Proteins of Serogroup B Vaccine
por: Marjuki, Henju, et al.
Publicado: (2019)

Commensal Neisseria Are Shared between Sexual Partners: Implications for Gonococcal and Meningococcal Antimicrobial Resistance
por: Van Dijck, Christophe, et al.
Publicado: (2020)

Pathogenic Neisseria Bind the Complement Protein CFHR5 via Outer Membrane Porins
por: Yee, Wearn-Xin, et al.
Publicado: (2022)

Binding thermodynamics of a glutamate transporter homologue
por: Reyes, Nicolas, et al.
Publicado: (2013)

The Effect of Human Factor H on Immunogenicity of Meningococcal Native Outer Membrane Vesicle Vaccines with Over-Expressed Factor H Binding Protein
por: Beernink, Peter T., et al.
Publicado: (2012)

Structure-based design of chimeric antigens for multivalent protein vaccines
por: Hollingshead, S., et al.
Publicado: (2018)

Factor H binding protein (fHbp)-mediated differential complement resistance of a serogroup C Neisseria meningitidis isolate from cerebrospinal fluid of a patient with invasive meningococcal disease
por: Facchetti, Alessandra, et al.
Publicado: (2021)

The Leishmania amazonensis TRF (TTAGGG repeat-binding factor) homologue binds and co-localizes with telomeres
por: da Silva, Marcelo S, et al.
Publicado: (2010)

The Gonococcal Genetic Island defines distinct sub-populations of Neisseria gonorrhoeae
por: Youngblom, Madison A., et al.
Publicado: (2023)

Factors contributing to the immunogenicity of meningococcal conjugate vaccines
por: Bröker, Michael, et al.
Publicado: (2016)

Gonococcal conjunctivitis after incomplete treatment of gonococcal urethritis
por: Wang, Mei-Fang, et al.
Publicado: (2019)

Gonococcal Invasion of Epithelial Cells Driven by P.IA, a Bacterial Ion Channel with GTP Binding Properties
por: van Putten, Jos P.M., et al.
Publicado: (1998)

Gonococcal Arthritis
por: Malhotra, S. L.
Publicado: (1950)

To What Extent Should We Rely on Antibiotics to Reduce High Gonococcal Prevalence? Historical Insights from Mass-Meningococcal Campaigns
por: Kenyon, Chris
Publicado: (2020)

Homologues of the RNA binding protein RsmA in Pseudomonas syringae pv. tomato DC3000 exhibit distinct binding affinities with non‐coding small RNAs and have distinct roles in virulence
por: Ge, Yixin, et al.
Publicado: (2019)

Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility
por: Caesar, Joseph JE, et al.
Publicado: (2014)

Role of the Gonococcal Neisserial Heparin Binding Antigen in Microcolony Formation, and Serum Resistance and Adherence to Epithelial Cells
por: Semchenko, Evgeny A, et al.
Publicado: (2020)

Functional Analysis of the Human Antibody Response to Meningococcal Factor H Binding Protein
por: Beernink, Peter T., et al.
Publicado: (2015)

Murine homologue of the human KIAA1199 is implicated in hyaluronan binding and depolymerization()
por: Yoshida, Hiroyuki, et al.
Publicado: (2013)

Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor
por: Spurny, Radovan, et al.
Publicado: (2015)

Identification and Therapeutic Potential of a Vitronectin Binding Region of Meningococcal Msf
por: Hill, Darryl J., et al.
Publicado: (2015)

NON-GONOCOCCAL URITHRITIS
Publicado: (1950)

Gonococcal Infection in the Male
Publicado: (1928)

Vaccine in Gonococcal Affections
Publicado: (1909)

Gonococcal Infection in the Male
Publicado: (1931)

Gonococcal breast abscess
por: Ceniceros, Ashley, et al.
Publicado: (2019)

Gonococcal Epididymitis in the Soldier
Publicado: (1919)

A Mouse Immunogenicity Model for the Evaluation of Meningococcal Conjugate Vaccines
por: Arunachalam, Arun B., et al.
Publicado: (2022)

The Meningococcal Vaccine Candidate Neisserial Surface Protein A (NspA) Binds to Factor H and Enhances Meningococcal Resistance to Complement
por: Lewis, Lisa A., et al.
Publicado: (2010)

The archaeal glutamate transporter homologue Glt(Ph) shows heterogeneous substrate binding
por: Reddy, Krishna D., et al.
Publicado: (2022)

Probing the Mechanisms of Inhibitors Binding to Presenilin Homologue Using Molecular Dynamics Simulations
por: Wang, Min, et al.
Publicado: (2023)

Endophthalmitis resulting from gonococcal keratoconjunctivitis
por: Bollam, R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qol9mt52cn216k6h68v9c9b6lg