An Anti-Human ICAM-1 Antibody Inhibits Rhinovirus-Induced Exacerbations of Lung Inflammation

Human rhinoviruses (HRV) cause the majority of common colds and acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD). Effective therapies are urgently needed, but no licensed treatments or vaccines currently exist. Of the 100 identified serotypes, ∼90% bind domain 1 of huma...

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Detalles Bibliográficos
Autores principales: Traub, Stephanie, Nikonova, Alexandra, Carruthers, Alan, Dunmore, Rebecca, Vousden, Katherine A., Gogsadze, Leila, Hao, Weidong, Zhu, Qing, Bernard, Katie, Zhu, Jie, Dymond, Michael, McLean, Gary R., Walton, Ross P., Glanville, Nicholas, Humbles, Alison, Khaitov, Musa, Wells, Ted, Kolbeck, Roland, Leishman, Andrew J., Sleeman, Matthew A., Bartlett, Nathan W., Johnston, Sebastian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731244/
https://www.ncbi.nlm.nih.gov/pubmed/23935498
http://dx.doi.org/10.1371/journal.ppat.1003520

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