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Geometric Attributes of Retaining Glycosyltransferase Enzymes Favor an Orthogonal Mechanism

Retaining glycosyltransferase enzymes retain the stereochemistry of the donor glycosidic linkage after transfer to an acceptor molecule. The mechanism these enzymes utilize to achieve retention of the anomeric stereochemistry has been a matter of much debate. Re-analysis of previously released struc...

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Detalles Bibliográficos
Autores principales: Schuman, Brock, Evans, Stephen V., Fyles, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731257/
https://www.ncbi.nlm.nih.gov/pubmed/23936487
http://dx.doi.org/10.1371/journal.pone.0071077