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AAV-Mediated Administration of Myostatin Pro-Peptide Mutant in Adult Ldlr Null Mice Reduces Diet-Induced Hepatosteatosis and Arteriosclerosis

Genetic disruption of myostatin or its related signaling is known to cause strong protection against diet-induced metabolic disorders. The translational value of these prior findings, however, is dependent on whether such metabolically favorable phenotype can be reproduced when myostatin blockade be...

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Detalles Bibliográficos
Autores principales: Guo, Wen, Wong, Siu, Bhasin, Shalender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731267/
https://www.ncbi.nlm.nih.gov/pubmed/23936482
http://dx.doi.org/10.1371/journal.pone.0071017