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Biomarker Report from the Phase II Lamotrigine Trial in Secondary Progressive MS – Neurofilament as a Surrogate of Disease Progression

OBJECTIVE: Lamotrigine trial in SPMS was a randomised control trial to assess whether partial blockade of sodium channels has a neuroprotective effect. The current study was an additional study to investigate the value of neurofilament (NfH) and other biomarkers in predicting prognosis and/or respon...

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Detalles Bibliográficos
Autores principales: Gnanapavan, Sharmilee, Grant, Donna, Morant, Steve, Furby, Julian, Hayton, Tom, Teunissen, Charlotte E., Leoni, Valerio, Marta, Monica, Brenner, Robert, Palace, Jacqueline, Miller, David H., Kapoor, Raj, Giovannoni, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731296/
https://www.ncbi.nlm.nih.gov/pubmed/23936370
http://dx.doi.org/10.1371/journal.pone.0070019