HIV-1 Envelope Glycoprotein Variable Loops Are Indispensable for Envelope Structural Integrity and Virus Entry

HIV-1 envelope (Env) glycoprotein is a trimer of heterodimer of gp120 and gp41, and derives from a trimeric glycoprotein precursor, gp160. Gp120 contains five conserved regions that are interspersed with 5 variable loop regions (V1–V5). Env variations in variable loop length and amino acid compositi...

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Detalles Bibliográficos
Autores principales: Yuan, Tingting, Li, Jingjing, Zhang, Mei-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731308/
https://www.ncbi.nlm.nih.gov/pubmed/23936354
http://dx.doi.org/10.1371/journal.pone.0069789

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