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Quantifying Selection Acting on a Complex Trait Using Allele Frequency Time Series Data

When selection is acting on a large genetically diverse population, beneficial alleles increase in frequency. This fact can be used to map quantitative trait loci by sequencing the pooled DNA from the population at consecutive time points and observing allele frequency changes. Here, we present a po...

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Detalles Bibliográficos
Autores principales: Illingworth, Christopher J.R., Parts, Leopold, Schiffels, Stephan, Liti, Gianni, Mustonen, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731369/
https://www.ncbi.nlm.nih.gov/pubmed/22114362
http://dx.doi.org/10.1093/molbev/msr289