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Quantifying Selection Acting on a Complex Trait Using Allele Frequency Time Series Data
When selection is acting on a large genetically diverse population, beneficial alleles increase in frequency. This fact can be used to map quantitative trait loci by sequencing the pooled DNA from the population at consecutive time points and observing allele frequency changes. Here, we present a po...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731369/ https://www.ncbi.nlm.nih.gov/pubmed/22114362 http://dx.doi.org/10.1093/molbev/msr289 |