A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-β1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis

Mitochondria dysfunction has been reported in various kidney diseases but how it leads to kidney fibrosis and how this is regulated is unknown. Here we found that mitochondrial uncoupling protein 2 (UCP2) was induced in kidney tubular epithelial cells after unilateral ureteral obstruction in mice an...

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Detalles Bibliográficos
Autores principales: Jiang, Lei, Qiu, Wenjing, Zhou, Yang, Wen, Ping, Fang, Li, Cao, Hongdi, Zen, Ke, He, Weichun, Zhang, Chenyu, Dai, Chunsun, Yang, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731557/
https://www.ncbi.nlm.nih.gov/pubmed/23515048
http://dx.doi.org/10.1038/ki.2013.80

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