Dose-related Increased Binding of Nickel to Chromatin Proteins; and Changes to DNA Concentration in the Liver of Guinea Pigs Treated with Nigerian Light Crude Oil

The alteration in nuclear DNA concentration and the concomitant binding of xenobiotics (alkylating agents, heavy metals, etc.) to chromatin constituents may adversely affect gene structure and/or function, and thus initiate carcinogenesis. Binding of nickel to chromatin DNA has been reported to caus...

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Detalles Bibliográficos
Autores principales: Oruambo, Ibiba F., Kachikwu, Stephanie, Idabor, Lauretta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731636/
https://www.ncbi.nlm.nih.gov/pubmed/17911659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731636/
https://www.ncbi.nlm.nih.gov/pubmed/17911659

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