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Endoplasmic reticulum stress preconditioning attenuates methylmercury-induced cellular damage by inducing favorable stress responses

We demonstrate that methylmercury (MeHg)-susceptible cells preconditioned with an inhibitor of endoplasmic reticulum (ER) Ca(2+)-ATPase, thapsigargin, showed resistance to MeHg cytotoxicity through favorable stress responses, which included phosphorylation of eukaryotic initiation factor 2 alpha (Ei...

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Detalles Bibliográficos
Autores principales:	Usuki, Fusako, Fujimura, Masatake, Yamashita, Akio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731649/ https://www.ncbi.nlm.nih.gov/pubmed/23907635 http://dx.doi.org/10.1038/srep02346

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