Cargando…

Conservation of 5-HT(1A) receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis

Firing activity of serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN) is controlled by inhibitory somatodendritic 5-HT(1A) autoreceptors. This autoinhibitory mechanism is implicated in the etiology of disorders of emotion regulation, such as anxiety disorders and depression, as well as in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Araragi, Naozumi, Mlinar, Boris, Baccini, Gilda, Gutknecht, Lise, Lesch, Klaus-Peter, Corradetti, Renato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731744/ https://www.ncbi.nlm.nih.gov/pubmed/23935583 http://dx.doi.org/10.3389/fphar.2013.00097

Ejemplares similares

Pharmacological Characterization of 5-HT(1A) Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons
por: Montalbano, Alberto, et al.
Publicado: (2015)

The role of the serotonin receptor subtypes 5-HT(1A) and 5-HT(7) and its interaction in emotional learning and memory
por: Stiedl, Oliver, et al.
Publicado: (2015)

Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease
por: Neumann, Joachim, et al.
Publicado: (2023)

Impacts of Brain Serotonin Deficiency following Tph2 Inactivation on Development and Raphe Neuron Serotonergic Specification
por: Gutknecht, Lise, et al.
Publicado: (2012)

The role of serotonin 5-HT(2A) receptors in memory and cognition
por: Zhang, Gongliang, et al.
Publicado: (2015)

Endogenous 5-HT outflow from chicken aorta by 5-HT uptake inhibitors and amphetamine derivatives
por: DELGERMURUN, Dugar, et al.
Publicado: (2015)

Serotonin homeostasis and serotonin receptors as actors of cortical construction: special attention to the 5-HT(3A) and 5-HT(6) receptor subtypes
por: Vitalis, Tania, et al.
Publicado: (2013)

Binding and functional structure-activity similarities of 4-substituted 2,5-dimethoxyphenyl isopropylamine analogues at 5-HT(2A) and 5-HT(2B) serotonin receptors
por: Hemanth, Prithvi, et al.
Publicado: (2023)

Regulatory mechanism of CCN2 production by serotonin (5-HT) via 5-HT(2A) and 5-HT(2B) receptors in chondrocytes
por: Hori, Ayaka, et al.
Publicado: (2017)

Biophysical validation of serotonin 5-HT(2A) and 5-HT(2C) receptor interaction
por: Felsing, Daniel E., et al.
Publicado: (2018)

5-HT(2A), 5-HT(1B/D), 5HT(3) and 5-HT(7) receptors as mediators of serotonin-induced direct contractile response of bovine airway smooth muscle
por: Da Costa Guevara, Darwin, et al.
Publicado: (2021)

5-HT Receptors and Temperature Homeostasis
por: Voronova, Irina P.
Publicado: (2021)

Expression Patterns of Serotonin Receptors 5-HT1A, 5-HT2A, and 5-HT3A during Human Fetal Lung Development
por: Nikolić, Jelena, et al.
Publicado: (2023)

Distribution of 5-HT(3), 5-HT(4), and 5-HT(7) Receptors Along the Human Colon
por: Yaakob, Nor S, et al.
Publicado: (2015)

Antidepressant activity: contribution of brain microdialysis in knock-out mice to the understanding of BDNF/5-HT transporter/5-HT autoreceptor interactions
por: Gardier, Alain M.
Publicado: (2013)

Anti-PTSD Effects of Hypidone Hydrochloride (YL-0919): A Novel Combined Selective 5-HT Reuptake Inhibitor/5-HT(1A) Receptor Partial Agonist/5-HT(6) Receptor Full Agonist
por: Liu, Wen-Gang, et al.
Publicado: (2021)

Review: 5-HT(1), 5-HT(2), 5-HT(3) and 5-HT(7) Receptors and their Role in the Modulation of Pain Response in the Central Nervous System
por: Cortes-Altamirano, Jose Luis, et al.
Publicado: (2018)

Serotonin 5-HT(2A )and 5-HT(6 )receptors in the prefrontal cortex of Alzheimer and normal aging patients
por: Lorke, Dietrich E, et al.
Publicado: (2006)

5HT(2A) and 5HT(2B) Receptors Contribute to Serotonin-Induced Vascular Dysfunction in Diabetes
por: Nelson, Peter M., et al.
Publicado: (2012)

Azologization of serotonin 5-HT(3) receptor antagonists
por: Rustler, Karin, et al.
Publicado: (2019)

Changes of Serotonin (5-HT), 5-HT2A Receptor, and 5-HT Transporter in the Sprague-Dawley Rats of Depression, Myocardial Infarction and Myocardial Infarction Co-exist with Depression
por: Liu, Mei-Yan, et al.
Publicado: (2015)

Dual inhibitory action of trazodone on dorsal raphe serotonergic neurons through 5-HT(1A) receptor partial agonism and α(1)-adrenoceptor antagonism
por: Montalbano, Alberto, et al.
Publicado: (2019)

Variation within the serotonin (5-HT) 5-HT(2C) receptor system aligns with vulnerability to cocaine cue reactivity
por: Anastasio, N C, et al.
Publicado: (2014)

Reduction of the serotonin 5-HT(1B) and 5-HT(2A) receptor-mediated contraction of human pulmonary artery by the combined 5-HT(1B) receptor antagonist and serotonin transporter inhibitor LY393558
por: Baranowska-Kuczko, Marta, et al.
Publicado: (2020)

5-HT6 receptor agonism facilitates emotional learning
por: Pereira, Marcela, et al.
Publicado: (2015)

Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link?
por: Guiard, Bruno P., et al.
Publicado: (2015)

Safety, Tolerability and Pharmacokinetics of the Serotonin 5-HT6 Receptor Antagonist, HEC30654, in Healthy Chinese Subjects
por: Li, Xiaojiao, et al.
Publicado: (2021)

Molecular and Pharmacological Characterization of Serotonin 5-HT(2α) and 5-HT(7) Receptors in the Salivary Glands of the Blowfly Calliphora vicina
por: Röser, Claudia, et al.
Publicado: (2012)

Maternal feeding patterns affect the offspring’s brain: focus on serotonin 5-HT(2C) and 5-HT(2A) receptors
por: Gawlińska, Kinga, et al.
Publicado: (2021)

Structural Insights into the Unexpected Agonism of Tetracyclic Antidepressants at Serotonin Receptors 5-HT1eR and 5-HT1FR
por: Zilberg, Gregory, et al.
Publicado: (2023)

Chronic Fluoxetine Impairs the Effects of 5-HT(1A) and 5-HT(2C) Receptors Activation in the PAG and Amygdala on Antinociception Induced by Aversive Situation in Mice
por: Baptista-de-Souza, Daniela, et al.
Publicado: (2020)

Human 5–HT(4) and 5–HT(7) Receptor Splice Variants: Are they Important?
por: Coupar, Ian M, et al.
Publicado: (2007)

Discriminating between 5-HT(3)A and 5-HT(3)AB receptors
por: Thompson, AJ, et al.
Publicado: (2013)

Control of Amygdala Circuits by 5-HT Neurons via 5-HT and Glutamate Cotransmission
por: Sengupta, Ayesha, et al.
Publicado: (2017)

Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT(2A )or 5-HT(2C )receptors
por: Seitz, Patricia K, et al.
Publicado: (2012)

5-HT1A agonists, 5-HT3 antagonists and benzodiazepines : their comparative behavioural pharmacology /
Publicado: (1991)

Neuronal localization of the 5-HT(2) receptor family in the amygdaloid complex
por: Bombardi, Cristiano
Publicado: (2014)

Hippocampal 5-HT(1A) Receptor and Spatial Learning and Memory
por: Glikmann-Johnston, Yifat, et al.
Publicado: (2015)

Capsaicin Is a Negative Allosteric Modulator of the 5-HT(3) Receptor
por: Nebrisi, Eslam El, et al.
Publicado: (2020)

5-HT3 and 5-HT4 antagonists inhibit peristaltic contractions in guinea-pig distal colon by mechanisms independent of endogenous 5-HT
por: Sia, Tiong C., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_p65ljt5ksrdg946sjcti1alhtp