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Conservation of 5-HT(1A) receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis
Firing activity of serotonin (5-HT) neurons in the dorsal raphe nucleus (DRN) is controlled by inhibitory somatodendritic 5-HT(1A) autoreceptors. This autoinhibitory mechanism is implicated in the etiology of disorders of emotion regulation, such as anxiety disorders and depression, as well as in th...
Autores principales: | Araragi, Naozumi, Mlinar, Boris, Baccini, Gilda, Gutknecht, Lise, Lesch, Klaus-Peter, Corradetti, Renato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731744/ https://www.ncbi.nlm.nih.gov/pubmed/23935583 http://dx.doi.org/10.3389/fphar.2013.00097 |
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