Cargando…

Influence of a priori Information, Designs, and Undetectable Data on Individual Parameters Estimation and Prediction of Hepatitis C Treatment Outcome

Hepatitis C viral kinetic analysis based on nonlinear mixed effect models can be used to individualize treatment. For that purpose, it is necessary to obtain precise estimation of individual parameters. Here, we evaluated by simulation the influence on Bayesian individual parameter estimation and ou...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, T H T, Guedj, J, Yu, J, Levi, M, Mentré, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731824/
https://www.ncbi.nlm.nih.gov/pubmed/23863865
http://dx.doi.org/10.1038/psp.2013.31