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Biosynthesis pathways of ginkgolides
The ginkgolides, acting as anti-platelet-activating factors, have been studied for many years. The biosynthetic pathway of ginkgolides is still far away from unveiling at the level of molecular genetics and biochemistry. There are at least 11 kinds of enzymes having been cloned from Ginkgo biloba L....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731879/ https://www.ncbi.nlm.nih.gov/pubmed/23922456 http://dx.doi.org/10.4103/0973-7847.112848 |
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author | Zeng, Zihan Zhu, Jianhua Chen, Lili Wen, Wei Yu, Rongming |
author_facet | Zeng, Zihan Zhu, Jianhua Chen, Lili Wen, Wei Yu, Rongming |
author_sort | Zeng, Zihan |
collection | PubMed |
description | The ginkgolides, acting as anti-platelet-activating factors, have been studied for many years. The biosynthetic pathway of ginkgolides is still far away from unveiling at the level of molecular genetics and biochemistry. There are at least 11 kinds of enzymes having been cloned from Ginkgo biloba L., which catalyze the formation of ginkgolides via a series of reactions. Some researchers have indicated that the addition of precursors and elicitors can influence the accumulation of ginkgolides in the suspension cell cultures of G. biloba. There are also other factors that can influence the production of ginkgolides. This review focuses on the aforementioned aspects to discuss the biosynthetic pathways of the ginkgolides. |
format | Online Article Text |
id | pubmed-3731879 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37318792013-08-06 Biosynthesis pathways of ginkgolides Zeng, Zihan Zhu, Jianhua Chen, Lili Wen, Wei Yu, Rongming Pharmacogn Rev Review Article The ginkgolides, acting as anti-platelet-activating factors, have been studied for many years. The biosynthetic pathway of ginkgolides is still far away from unveiling at the level of molecular genetics and biochemistry. There are at least 11 kinds of enzymes having been cloned from Ginkgo biloba L., which catalyze the formation of ginkgolides via a series of reactions. Some researchers have indicated that the addition of precursors and elicitors can influence the accumulation of ginkgolides in the suspension cell cultures of G. biloba. There are also other factors that can influence the production of ginkgolides. This review focuses on the aforementioned aspects to discuss the biosynthetic pathways of the ginkgolides. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3731879/ /pubmed/23922456 http://dx.doi.org/10.4103/0973-7847.112848 Text en Copyright: © Pharmacognosy Reviews http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Zeng, Zihan Zhu, Jianhua Chen, Lili Wen, Wei Yu, Rongming Biosynthesis pathways of ginkgolides |
title | Biosynthesis pathways of ginkgolides |
title_full | Biosynthesis pathways of ginkgolides |
title_fullStr | Biosynthesis pathways of ginkgolides |
title_full_unstemmed | Biosynthesis pathways of ginkgolides |
title_short | Biosynthesis pathways of ginkgolides |
title_sort | biosynthesis pathways of ginkgolides |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731879/ https://www.ncbi.nlm.nih.gov/pubmed/23922456 http://dx.doi.org/10.4103/0973-7847.112848 |
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