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Combination of siRNA-directed Gene Silencing With Cisplatin Reverses Drug Resistance in Human Non-small Cell Lung Cancer

One of the most challenging aspects of lung cancer therapy is the rapid acquisition of multidrug-resistant (MDR) phenotype. One effective approach would be to identify and downregulate resistance-causing genes in tumors using small interfering RNAs (siRNAs) to increase the sensitivity of tumor cells...

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Detalles Bibliográficos
Autores principales:	Ganesh, Shanthi, Iyer, Arun K, Weiler, Jan, Morrissey, David V, Amiji, Mansoor M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731892/ https://www.ncbi.nlm.nih.gov/pubmed/23900224 http://dx.doi.org/10.1038/mtna.2013.29

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