Cargando…

Specific Imaging of Inflammation with the 18kDa Translocator Protein Ligand DPA-714 in Animal Models of Epilepsy and Stroke

Inflammation is a pathophysiological hallmark of many diseases of the brain. Specific imaging of cells and molecules that contribute to cerebral inflammation is therefore highly desirable, both for research and in clinical application. The 18 kDa translocator protein (TSPO) has been established as a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harhausen, Denise, Sudmann, Violetta, Khojasteh, Uldus, Müller, Jochen, Zille, Marietta, Graham, Keith, Thiele, Andrea, Dyrks, Thomas, Dirnagl, Ulrich, Wunder, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732268/ https://www.ncbi.nlm.nih.gov/pubmed/23936336 http://dx.doi.org/10.1371/journal.pone.0069529

Ejemplares similares

In vivo Evaluation of Inflammatory Bowel Disease with the Aid of μPET and the Translocator Protein 18 kDa Radioligand [(18)F]DPA-714
por: Bernards, Nicholas, et al.
Publicado: (2014)

Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice
por: Harhausen, Denise, et al.
Publicado: (2010)

The translocator protein ligand [(18)F]DPA-714 images glioma and activated microglia in vivo
por: Winkeler, Alexandra, et al.
Publicado: (2012)

[(125) I]IodoDPA-713 Binding to 18 kDa Translocator Protein (TSPO) in a Mouse Model of Intracerebral Hemorrhage: Implications for Neuroimaging
por: Bonsack, Frederick, et al.
Publicado: (2018)

Single-cell resolution mapping of neuronal damage in acute focal cerebral ischemia using thallium autometallography
por: Stöber, Franziska, et al.
Publicado: (2014)

The 18 kDa Translocator Protein, Microglia and Neuroinflammation
por: Liu, Guo‐Jun, et al.
Publicado: (2014)

Antibody-mediated autoimmune encephalitis evaluated by (18)F-DPA714 PET/MRI
por: Shen, Ruinan, et al.
Publicado: (2022)

(18)F-DPA-714 PET Imaging for Detecting Neuroinflammation in Rats with Chronic Hepatic Encephalopathy
por: Kong, Xiang, et al.
Publicado: (2016)

Optimised GMP-compliant production of [(18)F]DPA-714 on the Trasis AllinOne module
por: Cybulska, Klaudia A., et al.
Publicado: (2021)

Quantification of [(18)F]DPA-714 binding in the human brain: initial studies in healthy controls and Alzheimer's disease patients
por: Golla, Sandeep S V, et al.
Publicado: (2015)

Could (18) F-DPA-714 PET imaging be interesting to use in the early post-stroke period?
por: Ribeiro, Maria-Joao, et al.
Publicado: (2014)

[(18)F]DPA-714 PET Imaging of AMD3100 Treatment in a Mouse Model of Stroke
por: Wang, Yu, et al.
Publicado: (2014)

Lack of neuroinflammation in the HIV-1 transgenic rat: an [(18)F]-DPA714 PET imaging study
por: Lee, Dianne E., et al.
Publicado: (2015)

[(18)F]DPA-714 PET Imaging Reveals Global Neuroinflammation in Zika Virus-Infected Mice
por: Kuszpit, Kyle, et al.
Publicado: (2017)

PET imaging of retinal inflammation in mice exposed to blue light using [(18)F]-DPA-714
por: Chen, Yuan, et al.
Publicado: (2022)

PET imaging of retinal inflammation in mice exposed to blue light using [(18)F]-DPA-714
por: Chen, Yuan, et al.
Publicado: (2023)

Evidence of neuroinflammation in fibromyalgia syndrome: a [(18)F]DPA-714 positron emission tomography study
por: Mueller, Christina, et al.
Publicado: (2023)

[(18)F]DPA-714 as a biomarker for positron emission tomography imaging of rheumatoid arthritis in an animal model
por: Pottier, Géraldine, et al.
Publicado: (2014)

Detection of Neuroinflammation in a Rat Model of Subarachnoid Hemorrhage Using [(18)F]DPA-714 PET Imaging
por: Thomas, Clément, et al.
Publicado: (2016)

Translocator Protein (18 kDa) Polymorphism (rs6971) in the Korean Population
por: Lee, Hyon, et al.
Publicado: (2022)

18 kDa Translocator Protein TSPO Is a Mediator of Astrocyte Reactivity
por: Tournier, Benjamin B., et al.
Publicado: (2023)

[(18)F]DPA-714: Direct Comparison with [(11)C]PK11195 in a Model of Cerebral Ischemia in Rats
por: Boutin, Hervé, et al.
Publicado: (2013)

Evaluation of PET Imaging Performance of the TSPO Radioligand [(18)F]DPA-714 in Mouse and Rat Models of Cancer and Inflammation
por: Zheng, Jinzi, et al.
Publicado: (2015)

In vivo assessment of neuroinflammation in progressive multiple sclerosis: a proof of concept study with [(18)F]DPA714 PET
por: Hagens, Marloes H. J., et al.
Publicado: (2018)

PET Imaging for Dynamically Monitoring Neuroinflammation in APP/PS1 Mouse Model Using [(18)F]DPA714
por: Hu, Wei, et al.
Publicado: (2020)

Initial experience with [(18)F]DPA-714 TSPO-PET to image inflammation in primary angiitis of the central nervous system
por: Backhaus, Philipp, et al.
Publicado: (2020)

[(18)F]PBR146 and [(18)F]DPA-714 in vivo Imaging of Neuroinflammation in Chronic Hepatic Encephalopathy Rats
por: Kong, Xiang, et al.
Publicado: (2021)

Direct Comparison of [(18)F]F-DPA with [(18)F]DPA-714 and [(11)C]PBR28 for Neuroinflammation Imaging in the same Alzheimer’s Disease Model Mice and Healthy Controls
por: López-Picón, Francisco R., et al.
Publicado: (2021)

De novo Neurosteroidogenesis in Human Microglia: Involvement of the 18 kDa Translocator Protein
por: Germelli, Lorenzo, et al.
Publicado: (2021)

Translocator protein 18 kDa regulates retinal neuron apoptosis and pyroptosis in glaucoma
por: Zeng, Zhou, et al.
Publicado: (2023)

Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation
por: Ouali, Boimpoundi Eunice Flavie, et al.
Publicado: (2020)

[(11)C]-DPA-713 and [(18)F]-DPA-714 as New PET Tracers for TSPO: A Comparison with [(11)C]-(R)-PK11195 in a Rat Model of Herpes Encephalitis
por: Doorduin, Janine, et al.
Publicado: (2009)

Longitudinal PET Imaging of Muscular Inflammation Using( 18)F-DPA-714 and (18)F-Alfatide II and Differentiation with Tumors
por: Wu, Chenxi, et al.
Publicado: (2014)

Microglia Loss and Astrocyte Activation Cause Dynamic Changes in Hippocampal [(18)F]DPA-714 Uptake in Mouse Models of Depression
por: Guo, Jiamei, et al.
Publicado: (2022)

Translocator Protein 18 kDa (TSPO) Is Regulated in White and Brown Adipose Tissue by Obesity
por: Thompson, Misty M., et al.
Publicado: (2013)

A Novel Interaction of Translocator Protein 18 kDa (TSPO) with NADPH Oxidase in Microglia
por: Loth, Meredith K., et al.
Publicado: (2020)

Translocator Protein 18 kDa (TSPO) as a Novel Therapeutic Target for Chronic Pain
por: Liu, Jie, et al.
Publicado: (2022)

The 18 kDa translocator protein is associated with microglia in the hippocampus of non-demented elderly subjects
por: Tournier, Benjamin B., et al.
Publicado: (2022)

(11)C-DPA-713 Versus (18)F-GE-180: A Preclinical Comparison of Translocator Protein 18 kDa PET Tracers to Visualize Acute and Chronic Neuroinflammation in a Mouse Model of Ischemic Stroke
por: Chaney, Aisling, et al.
Publicado: (2019)

Acute Morphine Exposure Increases the Brain Distribution of [(18)F]DPA-714, a PET Biomarker of Glial Activation in Nonhuman Primates
por: Auvity, Sylvain, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_lnsijl0apkkp0jtea44jmc34ph