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miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer
The activities of RNA-binding proteins are perturbed in several pathological conditions, including cancer. These proteins include tristetraprolin (TTP, ZFP36) and HuR (ELAVL1), which respectively promote the decay or stability of adenylate-uridylate-rich (AU-rich) mRNAs. Here, we demonstrated that i...
Autores principales: | Al-Ahmadi, Wijdan, Al-Ghamdi, Maha, Al-Souhibani, Norah, Khabar, Khalid SA |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732382/ https://www.ncbi.nlm.nih.gov/pubmed/23401122 http://dx.doi.org/10.1002/path.4178 |
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