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Nonfamilial, MPL S505N-Mutated Essential Thrombocythaemia

Mutations of MPL are present in a significant proportion of patients with the myeloproliferative neoplasms (MPN), primary myelofibrosis (PMF), and essential thrombocythaemia (ET). The most frequent of these mutations, W515L and W515K, occur in exon 10 of MPL, which encodes the receptor for thrombopo...

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Detalles Bibliográficos
Autores principales: Morrell, Ruth, Langabeer, Stephen E., Smyth, Liam, Perera, Meegahage, Crotty, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732633/
https://www.ncbi.nlm.nih.gov/pubmed/23970983
http://dx.doi.org/10.1155/2013/729327

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