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Raised Activity of L-Type Calcium Channels Renders Neurons Prone to Form Paroxysmal Depolarization Shifts
Neuronal L-type voltage-gated calcium channels (LTCCs) are involved in several physiological functions, but increased activity of LTCCs has been linked to pathology. Due to the coupling of LTCC-mediated Ca(2+) influx to Ca(2+)-dependent conductances, such as K(Ca) or non-specific cation channels, LT...
Autores principales: | Rubi, Lena, Schandl, Ulla, Lagler, Michael, Geier, Petra, Spies, Daniel, Gupta, Kuheli Das, Boehm, Stefan, Kubista, Helmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732764/ https://www.ncbi.nlm.nih.gov/pubmed/23695859 http://dx.doi.org/10.1007/s12017-013-8234-1 |
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