An insight into genetics of non-syndromic cleft palate

Our proband is a 29-year-old man, who is affected with soft cleft palate and hypernasality. A study of about six generations of this family pedigree shows that cleft palate has repeatedly occurred in males, with probably a X-linked recessive pattern of inheritance. Interestingly, the sister of the p...

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Autores principales: Nouri, Nayereh, Karimi, Padideh, Mansoor, Salehi, Memarzadeh, Mehrdad, Ganji, Hamid, Sedghi, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732890/
https://www.ncbi.nlm.nih.gov/pubmed/23930251
http://dx.doi.org/10.4103/2277-9175.107969
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author Nouri, Nayereh
Karimi, Padideh
Mansoor, Salehi
Memarzadeh, Mehrdad
Ganji, Hamid
Sedghi, Maryam
author_facet Nouri, Nayereh
Karimi, Padideh
Mansoor, Salehi
Memarzadeh, Mehrdad
Ganji, Hamid
Sedghi, Maryam
author_sort Nouri, Nayereh
collection PubMed
description Our proband is a 29-year-old man, who is affected with soft cleft palate and hypernasality. A study of about six generations of this family pedigree shows that cleft palate has repeatedly occurred in males, with probably a X-linked recessive pattern of inheritance. Interestingly, the sister of the proband is affected with hypernasality and she has an affected son. This is the first report of X-linked inheritance pattern of cleft palate in Iran.
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spelling pubmed-37328902013-08-08 An insight into genetics of non-syndromic cleft palate Nouri, Nayereh Karimi, Padideh Mansoor, Salehi Memarzadeh, Mehrdad Ganji, Hamid Sedghi, Maryam Adv Biomed Res Case Report Our proband is a 29-year-old man, who is affected with soft cleft palate and hypernasality. A study of about six generations of this family pedigree shows that cleft palate has repeatedly occurred in males, with probably a X-linked recessive pattern of inheritance. Interestingly, the sister of the proband is affected with hypernasality and she has an affected son. This is the first report of X-linked inheritance pattern of cleft palate in Iran. Medknow Publications & Media Pvt Ltd 2013-03-06 /pmc/articles/PMC3732890/ /pubmed/23930251 http://dx.doi.org/10.4103/2277-9175.107969 Text en Copyright: © 2013 Nouri. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
spellingShingle Case Report
Nouri, Nayereh
Karimi, Padideh
Mansoor, Salehi
Memarzadeh, Mehrdad
Ganji, Hamid
Sedghi, Maryam
An insight into genetics of non-syndromic cleft palate
title An insight into genetics of non-syndromic cleft palate
title_full An insight into genetics of non-syndromic cleft palate
title_fullStr An insight into genetics of non-syndromic cleft palate
title_full_unstemmed An insight into genetics of non-syndromic cleft palate
title_short An insight into genetics of non-syndromic cleft palate
title_sort insight into genetics of non-syndromic cleft palate
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732890/
https://www.ncbi.nlm.nih.gov/pubmed/23930251
http://dx.doi.org/10.4103/2277-9175.107969
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