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Effects of hemochromatosis and transferrin gene mutations on peripheral iron dyshomeostasis in mild cognitive impairment and Alzheimer's and Parkinson's diseases
Deregulation of iron metabolism has been observed in patients with neurodegenerative diseases. We have carried out a molecular analysis investigating the interaction between iron specific gene variants [transferrin (TF, P589S), hemochromatosis (HFE) C282Y and (H63D)], iron biochemical variables [iro...
Autores principales: | Mariani, S., Ventriglia, M., Simonelli, I., Spalletta, G., Bucossi, S., Siotto, M., Assogna, F., Melgari, J. M., Vernieri, F., Squitti, R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733023/ https://www.ncbi.nlm.nih.gov/pubmed/23935582 http://dx.doi.org/10.3389/fnagi.2013.00037 |
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