TALE-mediated modulation of transcriptional enhancers

We tested whether Transcription Activator-Like Effectors (TALEs) can mediate repression and activation of endogenous enhancers in the Drosophila genome. TALE-repressors (TALERs) targeting each of the five even-skipped (eve) “stripe” enhancers generated repression specifically of the focal stripes. T...

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Detalles Bibliográficos
Autores principales: Crocker, Justin, Stern, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733453/
https://www.ncbi.nlm.nih.gov/pubmed/23817068
http://dx.doi.org/10.1038/nmeth.2543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733453/
https://www.ncbi.nlm.nih.gov/pubmed/23817068
http://dx.doi.org/10.1038/nmeth.2543

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