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TALE-mediated modulation of transcriptional enhancers
We tested whether Transcription Activator-Like Effectors (TALEs) can mediate repression and activation of endogenous enhancers in the Drosophila genome. TALE-repressors (TALERs) targeting each of the five even-skipped (eve) “stripe” enhancers generated repression specifically of the focal stripes. T...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733453/ https://www.ncbi.nlm.nih.gov/pubmed/23817068 http://dx.doi.org/10.1038/nmeth.2543 |