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Systematic Verification of Upstream Regulators of a Computable Cellular Proliferation Network Model on Non-Diseased Lung Cells Using a Dedicated Dataset
We recently constructed a computable cell proliferation network (CPN) model focused on lung tissue to unravel complex biological processes and their exposure-related perturbations from molecular profiling data. The CPN consists of edges and nodes representing upstream controllers of gene expression...
Autores principales: | Belcastro, Vincenzo, Poussin, Carine, Gebel, Stephan, Mathis, Carole, Schlage, Walter K., Lichtner, Rosemarie B., Quadt-Humme, Sibille, Wagner, Sandra, Hoeng, Julia, Peitsch, Manuel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733638/ https://www.ncbi.nlm.nih.gov/pubmed/23926424 http://dx.doi.org/10.4137/BBI.S12167 |
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