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A network-based approach for predicting key enzymes explaining metabolite abundance alterations in a disease phenotype
BACKGROUND: The study of metabolism has attracted much attention during the last years due to its relevance in various diseases. The advance in metabolomics platforms allows us to detect an increasing number of metabolites in abnormal high/low concentration in a disease phenotype. Finding a mechanis...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733687/ https://www.ncbi.nlm.nih.gov/pubmed/23870038 http://dx.doi.org/10.1186/1752-0509-7-62 |