Requirement for the eIF4E Binding Proteins for the Synergistic Down-Regulation of Protein Synthesis by Hypertonic Conditions and mTOR Inhibition

The protein kinase mammalian target of rapamycin (mTOR) regulates the phosphorylation and activity of several proteins that have the potential to control translation, including p70S6 kinase and the eIF4E binding proteins 4E-BP1 and 4E-BP2. In spite of this, in exponentially growing cells overall pro...

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Detalles Bibliográficos
Autores principales: Clemens, Michael J., Elia, Androulla, Morley, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733773/
https://www.ncbi.nlm.nih.gov/pubmed/23940704
http://dx.doi.org/10.1371/journal.pone.0071138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733773/
https://www.ncbi.nlm.nih.gov/pubmed/23940704
http://dx.doi.org/10.1371/journal.pone.0071138

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