Cargando…
Topical Rosiglitazone Is an Effective Anti-Scarring Agent in the Cornea
Corneal scarring remains a major cause of blindness world-wide, with limited treatment options, all of which have side-effects. Here, we tested the hypothesis that topical application of Rosiglitazone, a Thiazolidinedione and ligand of peroxisome proliferator activated receptor gamma (PPARγ), can ef...
Autores principales: | Huxlin, Krystel R., Hindman, Holly B., Jeon, Kye-Im, Bühren, Jens, MacRae, Scott, DeMagistris, Margaret, Ciufo, David, Sime, Patricia J., Phipps, Richard P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733781/ https://www.ncbi.nlm.nih.gov/pubmed/23940641 http://dx.doi.org/10.1371/journal.pone.0070785 |
Ejemplares similares
-
Corneal myofibroblasts inhibit regenerating nerves during wound healing
por: Jeon, Kye-Im, et al.
Publicado: (2018) -
Blocking Mitochondrial Pyruvate Transport Alters Corneal Myofibroblast Phenotype: A New Target for Treating Fibrosis
por: Jeon, Kye-Im, et al.
Publicado: (2023) -
Keratocyte Apoptosis and Not Myofibroblast Differentiation Mark the Graft/Host Interface at Early Time-Points Post-DSAEK in a Cat Model
por: Weis, Adam J., et al.
Publicado: (2013) -
How scars shape the neural landscape: Key molecular mediators of TGF-β1’s anti-neuritogenic effects
por: Jeon, Kye-Im, et al.
Publicado: (2020) -
Defining the Role of Mitochondrial Fission in Corneal Myofibroblast Differentiation
por: Jeon, Kye-Im, et al.
Publicado: (2022)